Progress in Copper-Catalyzed Asymmetric Allylic Alkylation Reaction
نویسندگان
چکیده
منابع مشابه
Dynamic kinetic asymmetric transformation in copper catalyzed allylic alkylation.
The first dynamic kinetic asymmetric transformation in copper catalyzed allylic alkylation is reported, with enantioselectivities up to 92%.
متن کاملChalcogen-Containing Oxazolines in the Palladium-Catalyzed Asymmetric Allylic Alkylation
The search for new ligands in asymmetric catalysis is a field of continuing interest. To facilitate practical applications, new ligands should be easy to prepare from simple and easily available starting materials. In this context, the use of chiral nitrogen compounds bearing an organochalcogen moiety and their metal complexes have gained increased importance in the field of asymmetric catalysi...
متن کاملEfficient palladium-catalyzed asymmetric allylic alkylation of ketones and aldehydes.
Palladium-catalyzed asymmetric allylic alkylation of ketones, via enamines generated in situ as nucleophiles, were carried out smoothly with chiral metallocene-based P,N-ligands. Under the same conditions, however, reactions of aldehydes could hardly be observed. Subsequently, this obstacle was resolved by using chiral metallocene-based P,P-ligands. Both ketones and aldehydes afforded excellent...
متن کاملSynthesis of (-)-Delta9-trans-tetrahydrocannabinol: stereocontrol via Mo-catalyzed asymmetric allylic alkylation reaction.
[reaction: see text] Delta9-THC is synthesized in enantiomericaly pure form, where all of the stereochemistry is derived from the molybdenum-catalyzed asymmetric alkylation reaction of the extremely sterically congested bis-ortho-substituted cinnamyl carbonate in high regio- and enantioselectivity.
متن کاملOrganocatalytic peroxy-asymmetric allylic alkylation.
The peroxy-asymmetric allylic alkylation of hydroperoxyalkanes with Morita-Baylis-Hillman carbonates was catalysed by modified cinchona alkaloids (up to 93% ee), from which chiral alpha-methylene-beta-hydroxy esters could be efficiently derived.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chinese Journal of Organic Chemistry
سال: 2012
ISSN: 0253-2786
DOI: 10.6023/cjoc1110071